HomePRODUCTSLife ScienceOsrhAAT Recombinant Human Alpha-1 Antitrypsin

OsrhAAT Recombinant Human Alpha-1 Antitrypsin

Cell Culture Grade

 

• Source: Rice Grain (Oryza Sativa)

• Cat No: HYC006M01

• Appearance: White loose body

• Package Size: 10mg, 100mg

Molecular weight: 46.7 kDa

Activity: 3~5 mg OsrhAAT can inhibit 1 mg PPE (pancreatic porcine elastase) with an activity of 10.8 IU/mg

Purity: ≥ 90.0% by SDS-PAGE

Endotoxin: < 1.0 EU/mg

If you would like to obtain the following data and information, please click below to "Get Document":
  • Detailed Description
  • FAQ
  • Product Description

    Human Alpha-1 Antitrypsin (AAT) is a secreted serine protease inhibitor. It protects tissues from enzymes released by inflammatory cells, especially neutrophil elastase. In its absence, neutrophil elastase is free to break down elastin, which contributes to lung elasticity, resulting in respiratory complications such as emphysema or COPD (chronic obstructive pulmonary disease) in adults, and cirrhosis in adults or children.OsrhAAT, purified by chromatography from rice endosperm and then lyophilized with mannitol as a stabilizer, contains 384 amino acids. The rice endosperm platform enables production at hundreds-of-grams scale to meet your bioprocessing needs.

    Advantages

    Chemically Defined & Animal-Free;
    High Batch-to-Batch Consistancy;
    Stable Bulk Supply
    cGMP Manufactured

    Application

    Cell culture,Antigen,Test control

    Preparation and Storage

    Reconstitution: Recommend to reconstitute OsrhAAT at 100-200μg/ml in sterile water.Further dilutions can be made in other aqueous buffer.
    Storage: Stored at temperature -20°C for at least 36 months.

    Please avoid repeated freeze-thaw cycles.

    FOR RESEARCH, LABORATORY AND MANUFACTURE USE ONLY. NOT INTENDED FOR DIRECT USE ON HUMANS.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

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