rhlGF-1 LR3 Recombinant Human Insulin-like Growth Factor LR3

Product Description

Human Insulin-like growth factor-1 (hIGF-1) is a hormone similar in molecular structure to insulin. It primarily functions by binding to its specific receptor, the insulin-like growth factor 1 receptor (IGF1R). IGF-1 is one of the most potent natural activators of the AKT signaling pathway, which stimulates cell growth and proliferation and inhibits cell apoptosis.rhIGF-1 LR3 (rhIGF-1 Long Arg3) is an 83-amino-acid analog of IGF-1. It comprises the complete human IGF-1 sequence with an arginine (Arg) substituted for glutamic acid (Glu) at position 3 (hence R3), plus a 13-amino-acid extension peptide at the N-terminus.

The rhIGF-1 LR3, purified by chromatography from E. coli or CHO cells, then lyophilized with Mannitol, has much higher stability and biological activity. The manufacture capability at hundreds of grams scales can meet your large bioprocessing needs.

Advantages

Chemically Defined & Animal-Free;
High Batch-to-Batch Consistancy;
Stable Bulk Supply
cGMP Manufactured

Application

Cell Culture
IVD Reagent Antigens

Preparation and Storage

Reconstitution: Recommend to reconstitute rhIGF-1 LR3 at 100-200μg/ml concentration in sterile water. Further dilutions can be made in other aqueous buffer.
Storage: Stored at temperature -20°C for at least 36 months.

Please avoid repeated freeze-thaw cycles.

FOR RESEARCH, LABORATORY AND MANUFACTURE USE ONLY. NOT INTENDED FOR DIRECT USE ON HUMANS.