Keratinocyte growth factor (KGF) , also known as FGF-7, is a member of FGF family. It is a cytokine discovered in the culture supernatant of embryonic lung fibroblasts. KGF, an effective epithelial cell-specific growth factor, is secreted by mesenchymal cells and its receptor is distributed in epithelial cells. Its mitotic activity is mainly manifested in keratinocytes, which can specifically stimulate the proliferation, migration and differentiation of epithelial cells. It also closely relate to organ development, wound healing, tumorigenesis and immune reconstruction etc.
OsrhKGF, expressed in the rice endosperm platform and purified by chromatography, is animal component free and has high biological activity. The rice endosperm platform makes the manufacture capability at hundreds of gram scales to meet your bulk bioprocessing needs.
Biological Activity: The ED50 is ≤1ng/ml determined by a cell proliferation assay using MCF-7, corresponding to a specific activity of ≥1×105 Units/mg.
Applications: Mammalian cell culture
Cosmetic and beauty care
Storage and Handling:
Stored at temperatures -20℃ for at least 12 months. It is recommended to reconstitute the lyophilized OsrhKGF in sterile water. Use as soon as possible after opening. Please avoid freeze-thaw cycles.
FOR RESEARCH, LABORATORY AND MANUFACTURE USE ONLY. NOT INTENDED FOR DIRECT USE ON HUMANS.